产品货号：
Z35415
中文名称：
OPG/TNFRSF11B抗体
英文名称：
Anti-OPG/TNFRSF11B Antibody (Clone#27T13)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OPG/TNFRSF11B Antibody (Clone#27T13) |
| 指标别名 | TNF receptor superfamily member 11b;OCIF;OPG;PDB5;TR1;TNFRSF11B |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IHC,ICC/IF |
| 基因名称 | TNFRSF11B |
| 克隆号 | 27T13 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Osteoprotegerin |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B),also known as OPG,is a protein that in humans is encoded by the TNFRSF11B gene.OPG is a cytokine receptor,and a member of the tumor necrosis factor (TNF) receptor superfamily.By analysis of radiation hybrids,TNFRSF11B gene was mapped to chromosome 8q24.OPG is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL).By binding RANKL,OPG inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes,and a key regulator of inflammation,innate immunity,and cell survival and differentiation.OPG binding to RANKL on osteoblast/stromal cells,blocks the RANKL-RANK ligand interaction between osteoblast/stromal cells and ostepclast precursors. |
| Uniprot ID | O00300 |
| 推荐稀释比 | IHC 1:50～1:200 ICC/IF 1:50～1:200 |
相关搜索：OPG/TNFRSF11B抗体，OPG抗体，TNFRSF11B单抗，Anti-OPG/TNFRSF11B Antibody (Clone#27T13)